KIMM develops technology for detecting injection of medication to prevent medical accidents related to analgesic drug infusion

Press releases may be edited for formatting or style | January 31, 2024 Infusion Pumps
Excessive administration of analgesic drugs frequently results in medical accidents. To prevent the occurrence of these accidents, a drug infusion pump featuring a technology for safely detecting medication administration has been developed for the first time in the world.

The research team led by Senior Researcher Dong-kyu Lee of the Korea Institute of Machinery and Materials (President Seog-hyun Ryu, hereinafter referred to as KIMM), an institute under the jurisdiction of the Ministry of Science and ICT, has succeeded in developing the technology for customized sensor modules capable of measuring the extremely low flow rate of analgesic drug infusion pumps as well as the existence of bubbles in these pumps. A safe drug infusion pump system equipped with this sensor module is currently being developed for mass production by Unimedics (Representative Director Joo-seok Yang), one of Korea’s most renowned manufacturers of medication injectors.

Meanwhile, this technology was selected as the “2023 Outstanding Research Achievements by Government-funded Research Institutions(Nov, 29, 2023)” in recognition of the research achievements related thereto, including publication in an SCI journal*, filing of multiple patent applications (four (4) in Korea, one (1) in the United States), and technology transfers.
*Title of publication: “Sensitive and reliable thermal micro-flow sensor for a drug infusion” (Sensors and Actuators A: physical, date of publication: April 27, 2020)

While narcotic analgesics are administered for post-operative pain management at an extremely low flow rate of 1 to 2 mL/h, the KIMM developed a new thermal micro-flow sensor using a micro-heater and multiple temperature sensors in order to accurately measure such low flow rates. The research team succeeded in measuring the extremely low flow rates by combining the cooling effect of the microheater caused by heat loss with the heating effect that the microheater has on the fluid.

Additionally, in line with the revised regulations of the FDA that now require bubble sensors to be included in drug infusion pumps, the newly developed infusion pumps are equipped with temperature sensors at both ends of the assembled tube, and these sensors are capable of detecting bubbles by using the difference in heat diffusion depending on the air or liquid inside the tube. In particular, by attaching the sensor to the drug injection tube, the flow rate and bubbles can be measured non-intrusively on the outer surface of the tube. By allowing for the reuse of sensors, this can help to resolve the issues associated with the limited medical fees for medical disposables.

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